nkhani

Splanchnic inversion (kuphatikizapo inversion yonse ya splanchnic [dextrocardia] ndi partial splanchnic inversion [levocardia]) ndizosowa kobadwa nako kakulidwe kachilendo komwe njira yogawa splanchnic kwa odwala ndi yosiyana ndi ya anthu wamba. Tidawona chiwonjezeko chachikulu cha milandu ya fetal visceral inversion yomwe idatsimikiziridwa ndi ultrasound kuchipatala chathu miyezi ingapo itathetsedwa kwa mfundo ya "zero clearance" ya COVID-19 ku China.

Powunika deta yachipatala kuchokera ku malo awiri oberekera m'madera osiyanasiyana a China, tinazindikira zochitika za fetal visceral inversion kuyambira January 2014 mpaka July 2023. M'miyezi isanu ndi iwiri yoyambirira ya 2023, zochitika za inversion mkati (kawirikawiri prenatal ultrasonography ndi matenda pafupifupi 20 mpaka 24 zaka zachipatala) popanda kusintha kwa dokotala m'masabata anayi kapena kusintha kwa gesta. nthawi zambiri kuposa kuchuluka kwapachaka kwa 2014-2022 m'malo onse awiri (Chithunzi 1).

Chiwerengero cha visceral inversion chinafika mu April 2023 ndipo chinakhalabe chokwera mpaka June 2023. Kuyambira January 2023 mpaka July 2023, milandu 56 ya splanchnosis inapezeka (52 total splanchnosis ndi 4 partial splanchnosis). Kuchuluka kwa matenda a SARS-CoV-2 kudakwera pambuyo pakuthetsedwa kwa mfundo za COVID-19 "zero clearance", kutsatiridwa ndi kuchuluka kwa milandu yosinthika ya visceral. Akuti kuchuluka kwa matenda a SARS-CoV-2 kudayamba koyambirira kwa Disembala 2022, kudakwera pafupifupi Disembala 20, 2022, ndipo kudatha koyambirira kwa February 2023, zomwe zidakhudza pafupifupi 82% ya anthu aku China. Ngakhale palibe mfundo zomwe zingaganizidwe pazachiwopsezo, zomwe tikuwona zikuwonetsa mgwirizano womwe ungakhalepo pakati pa matenda a SARS-CoV-2 ndi inversion ya fetal visceral, yomwe ikufunika kupitilira apo.kuphunzira.

Chithunzi A chikuwonetsa zochitika zotsimikizika za kusintha kwa fetal splanchnic m'malo awiri oberekera kuyambira Januwale 2014 mpaka July 2023. Ziwerengero zomwe zili pamwamba pa bar chart zikuwonetsa chiwerengero chonse cha milandu chaka chilichonse. Zochitika zidanenedwa ngati kuchuluka kwa milandu pa amayi 10,000 apakati omwe adapimidwa ndi ultrasound. Chithunzi B chikuwonetsa kuchuluka kwa milandu yotsimikizika ya visceral inversion kuyambira Januware 2023 mpaka Julayi 2023 ku China Welfare Society International Peace Maternal and Child Health Hospital (IPMCH) ku Shanghai ndi Hunan Provincial Maternal and Child Health Hospital (HPM) ku Changsha.

Congenital visceral inversion imalumikizidwa ndi kugawa kwa mahomoni a morphogenetic ndi kumanzere kumanja kwa cilium kukanika koyambirira kwa chiberekero cha embryo kumanzere-kumanja axis asymmetry. Ngakhale kufalikira koyimirira kwa SARS-CoV-2 kukadali kotsutsana, matenda a mwana wosabadwayo ali ndi pakati amatha kukhudza chitukuko cha fetal visceral asymmetrical. Kuphatikiza apo, SARS-CoV-2 imatha kukhudza mosadukiza ntchito yapakati yakumanzere yakumanja kudzera mu kuyankha kwake kwapakati pa kutupa kwa amayi, motero kulepheretsa kukula kwa visceral asymmetrical. M'maphunziro amtsogolo, kusanthula kwina ndikofunikira kutsimikizira kuti zovuta zama genetic zomwe zimagwirizanitsidwa ndi ciliary dyskinesia zomwe mwina sizinawonekere pakuwunika kwa majini obadwa nawo sizimayambitsa milanduyi, ndikuwunikanso zomwe zingachitike pazinthu zachilengedwe pakuwonjezeka kwa ma visceral inpositions. Zindikirani kuti ngakhale kuchuluka kwa visceral inversion kudakwera m'malo awiri oberekera pambuyo pakuchita opaleshoni ya SARS-CoV-2, zochitika zachipatala za visceral inversion zikadali zosowa kwambiri.